Research Article
Open access
Published on 21 February 2025
Download pdf
Xu,Y. (2025). Instrumental Behavior in Pavlovian-instrumental Transfer for Depression Therapy. Communications in Humanities Research,56,24-30.
Export citation

Instrumental Behavior in Pavlovian-instrumental Transfer for Depression Therapy

Yanwei Xu *,1,
  • 1 Suchow University

* Author to whom correspondence should be addressed.

https://doi.org/10.54254/2753-7064/2024.21058

Abstract

The mental condition is closely linked with people’s instrumental behavior, which allows us to adapt to the external environment. Rely on the positive valence system, the habits and goal or value seeking behavior is linked with the instrumental behavior and the influence of environmental cues. While depression patients build up an aversive Pavlovian-instrumental transfer and form a biased emotional state. The Pavlovian-to-instrumental transfer (PIT) was influenced by the environment and was reflected in biological chemistry level. Also, in the safety learning and exposure therapy, instrumental behavior has become a fundamental factor of generation of safety signals to help ease fear and anxiety. It makes exposure therapy possible. All of them are revealing that by changing instrumental behavior, it may be able to change patients’ mental condition and contribute to depression therapy. In the future, simple and effective instrumental behavior may be able to get into therapy and recover procedure of all kinds of mental disorders.

Keywords

instrumental behavior, depression therapy, environmental cues, Pavlovian-instrumental transfer (PIT), positive valence system

[1]. Cartoni, E., Balleine, B., & Baldassarre, G. (2016). Appetitive Pavlovian-instrumental transfer: A review. Neuroscience and Biobehavioral Reviews, 71, 829-848. https://doi.org/10.1016/j.neubiorev.2016.09.020

[2]. Nord, C. L., Lawson, R. P., Huys, Q. J. M., Pilling, S., & Roiser, J. P. (2018). Depression is associated with enhanced aversive Pavlovian control over instrumental behavior. Scientific Reports, 8(1), 12582-10. https://doi.org/10.1038/s41598-018-30828-5

[3]. Metts, A., Arnaudova, I., Staples-Bradley, L., Sun, M., Zinbarg, R., Nusslock, R., Wassum, K. M., & Craske, M. G. (2022). Disruption in Pavlovian-instrumental transfer as a function of depression and anxiety. Journal of Psychopathology and Behavioral Assessment, 44(2), 481-495. https://doi.org/10.1007/s10862-021-09941-9

[4]. Geurts, D. E. M., Huys, Q. J. M., den Ouden, H. E. M., & Cools, R. (2013). Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of Neuroscience, 33(48), 18932–18939. https://doi.org/10.1523/JNEUROSCI.2749-13.2013

[5]. Thurston, M. D., & Cassaday, H. J. (2022). Safety Learning in Anxiety, Pavlovian Conditioned Inhibition and COVID Concerns. Frontiers in Psychology, 13, 866771–866771. https://doi.org/10.3389/fpsyg.2022.866771

[6]. Burton, T. J., & Balleine, B. W. (2022). The positive valence system, adaptive behavior, and the origins of reward. Emerging Topics in Life Sciences, 6(5), 501–513. https://doi.org/10.1042/ETLS20220007

[7]. Corr P. J. (2004). Reinforcement sensitivity theory and personality. Neuroscience and biobehavioral reviews, 28(3), 317–332. https://doi.org/10.1016/j.neubiorev.2004.01.005

[8]. Cools, R., Robinson, O. J., & Sahakian, B. (2008). Acute tryptophan depletion in healthy volunteers enhances punishment prediction but does not affect reward prediction. Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology, 33(9), 2291–2299. https://doi.org/10.1038/sj.npp.1301598

[9]. Cools, R., Roberts, A. C., & Robbins, T. W. (2008). Serotoninergic regulation of emotional and behavioral control processes. Trends in cognitive sciences, 12(1), 31–40. https://doi.org/10.1016/j.tics.2007.10.011

[10]. Daw, N. D., & Dayan, P. (2014). The algorithmic anatomy of model-based evaluation. Philosophical Transactions of the Royal Society B: Biological Sciences, 369(1655), 20–20130478. https://doi.org/10.1098/rstb.2013.0478

[11]. Anderson, M. L., & Oates, T. (2007). A Review of Recent Research in Metareasoning and Metalearning. The AI Magazine, 28(1), 7–16. https://doi.org/10.1609/aimag.v28i1.2025

[12]. Huys, Q. J. M., Daw, N. D., & Dayan, P. (2015). Depression: A Decision-Theoretic Analysis. Annual Review of Neuroscience, 38(1), 1–23. https://doi.org/10.1146/annurev-neuro-071714-033928

[13]. Huys, Q. J. M., Gölzer, M., Friedel, E., Heinz, A., Cools, R., Dayan, P., & Dolan, R. J. (2016). The specificity of Pavlovian regulation is associated with recovery from depression. Psychological Medicine, 46(5), 1027–1035. https://doi.org/10.1017/S0033291715002597

[14]. Garbusow, M., Ebrahimi, C., Riemerschmid, C., Daldrup, L., Rothkirch, M., Chen, K., Chen, H., Belanger, M. J., Hentschel, A., Smolka, M. N., Heinz, A., Pilhatsch, M., & Rapp, M. A. (2022). Pavlovian-to-instrumental transfer across mental disorders: A review. Neuropsychobiology, 81(5), 418-437. https://doi.org/10.1159/000525579

[15]. Lopizzo, N., Bocchio Chiavetto, L., Cattane, N., Plazzotta, G., Tarazi, F. I., Pariante, C. M., Riva, M. A., & Cattaneo, A. (2015). Gene-environment interaction in major depression: focus on experience-dependent biological systems. Frontiers in Psychiatry, 6, 68–68. https://doi.org/10.3389/fpsyt.2015.00068

Cite this article

Xu,Y. (2025). Instrumental Behavior in Pavlovian-instrumental Transfer for Depression Therapy. Communications in Humanities Research,56,24-30.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

Disclaimer/Publisher's Note

The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of EWA Publishing and/or the editor(s). EWA Publishing and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

About volume

Volume title: Proceedings of 3rd International Conference on Interdisciplinary Humanities and Communication Studies

Conference website: https://2024.icihcs.org/
ISBN:978-1-83558-977-9(Print) / 978-1-83558-978-6(Online)
Conference date: 29 November 2024
Editor:Heidi Gregory-Mina
Series: Communications in Humanities Research
Volume number: Vol.56
ISSN:2753-7064(Print) / 2753-7072(Online)

© 2024 by the author(s). Licensee EWA Publishing, Oxford, UK. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. Authors who publish this series agree to the following terms:
1. Authors retain copyright and grant the series right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this series.
2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the series's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this series.
3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See Open access policy for details).