
Brain-computer interface applications in the aging population with Alzheimer’s and Parkinson’s disease
- 1 SWJTU-Leeds Joint School, Southwest Jiaotong University-University of Leeds, Chengdu, Sichuan, 611700, China
* Author to whom correspondence should be addressed.
Abstract
The rapidly aging population faces increasing prevalence of neurodegenerative conditions like Alzheimer's Disease (AD) and Parkinson's Disease (PD), which significantly impair cognitive and motor functions. There is an urgent need for increased research, awareness, and development of effective treatments to mitigate their impact on the affected individuals and their families. This paper delves into the history, mechanisms, and applications of brain-computer interfaces (BCIs) as innovative solutions to mitigate these impacts. BCIs enable direct brain-to-device communication, circumventing conventional neuromuscular routes. We highlight how neurofeedback and neuroplasticity facilitated by BCIs not only restore motor skills and cognitive functions but also enhance the overall quality of life for sufferers. Through applications in cognitive training, motor assistance, and advanced communication aids, BCIs present a significant promise despite the ethical and practical challenges they pose. The continual advancement of this technology promises to a future when its incorporation into treatment plans will be widely used and provide significant advantages for those with PD and AD.
Keywords
Brain Computer Interface, Alzheimer's Disease, Parkinson's Disease.
[1]. Young, M. J., Lin, D. J., & Hochberg, L. R. (2021). Brain–Computer interfaces in neurorecovery and neurorehabilitation. In Seminars in neurology, 41(02), 206-216.
[2]. Wolpaw, J. R., Millan, J. D. R., & Ramsey, N. F. (2020). Brain-computer interfaces: Definitions and principles. Handbook of clinical neurology, 168, 15-23.
[3]. Mudgal, S. K., Sharma, S. K., Chaturvedi, J., & Sharma, A. (2020). Brain computer interface advancement in neurosciences: Applications and issues. Interdisciplinary Neurosurgery, 20, 100694.
[4]. Jackson, A., & Zimmermann, J. B. (2012). Neural interfaces for the brain and spinal cord—restoring motor function. Nature Reviews Neurology, 8(12), 690-699.
[5]. Alzheimer’s Disease Fact Sheet, National Institute on Aging. URL: https://www.nia.nih.gov/health/alzheimers-and-dementia/alzheimers-disease-fact-sheet. Last Accessed: 2024/08/04.
[6]. GBD Compare, Institute for Health Metrics and Evaluation. URL: http://vizhub.healthdata.org/gbd-compare. Last Accessed: 2024/08/04.
[7]. Taya, F., Sun, Y., Babiloni, F., Thakor, N., & Bezerianos, A. (2015). Brain enhancement through cognitive training: a new insight from brain connectome. Frontiers in systems neuroscience, 9, 44-63.
[8]. Oh, S. J., & Ryu, J. N. (2018). The effect of brain-computer interface-based cognitive training in patients with dementia. Journal of the Korean Society of Physical Medicine, 13(4), 59-65.
[9]. Carelli, L., Solca, F., Faini, A., Meriggi, P., et, al. (2017). Brain‐computer interface for clinical purposes: Cognitive assessment and rehabilitation. BioMed research international, 2017(1), 1695290.
[10]. Lin, P. J., Ku, H. C., & Lin, L. L. (2024). Design and Development of Cognitive Training Systems Based on Extended Reality and BCI Technology. In 2024 IEEE 7th Eurasian Conference on Educational Innovation, 4-7.
[11]. Denggui, F., Suyu, L., Zhihui, W., Qingyun. W., (2015). The control effect of deep brain stimulation on the dynamics of neuronal networks in Parkinson's disease (Chinese). In Proceedings of the 15th National Conference on Nonlinear Vibration and the 12th National Conference on Nonlinear Dynamics and Stability of Motion, 1.
[12]. Grimaldi, G., & Manto, M. (2010). Old and emerging therapies of human tremor. Clinical Medicine Insights: Therapeutics, 2, 2999.
[13]. Ferrazoli, N., Donadon, C., Rezende, A., Skarzynski, P. H., & Sanfins, M. D. (2022). The application of P300-long-latency auditory-evoked potential in Parkinson disease. International archives of otorhinolaryngology, 26(01), 158-166.
[14]. Rosenfeld, J. V., & Wong, Y. T. (2017). Neurobionics and the brain–computer interface: current applications and future horizons. Medical Journal of Australia, 206(8), 363-368.
[15]. Shi, T., Ren, L., & Cui, W. (2019). Feature extraction of brain–computer interface electroencephalogram based on motor imagery. IEEE Sensors Journal, 20(20), 11787-11794.
[16]. Ren, S., Wang, W., Hou, Z. G., Liang, X., Wang, J., & Shi, W. (2020). Enhanced motor imagery based brain-computer interface via FES and VR for lower limbs. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 28(8), 1846-1855.
[17]. Chen, X., Wang, Y., Nakanishi, M., Gao, X., Jung, T. P., & Gao, S. (2015). High-speed spelling with a noninvasive brain–computer interface. Proceedings of the national academy of sciences, 112(44), E6058-E6067.
[18]. Ebrahimi, T., Vesin, J. M., & Garcia, G. (2003). Brain-computer interface in multimedia communication. IEEE signal processing magazine, 20(1), 14-24.
[19]. Lazarou, I., Nikolopoulos, S., Petrantonakis, P. C., Kompatsiaris, I., & Tsolaki, M. (2018). EEG-based brain–computer interfaces for communication and rehabilitation of people with motor impairment: a novel approach of the 21st Century. Frontiers in human neuroscience, 12, 14.
[20]. Benabid, A. L. (2003). Deep brain stimulation for Parkinson’s disease. Current opinion in neurobiology, 13(6), 696-706.
[21]. Yue, C. (2023). Privacy and Ethical Concerns of Brain-Computer Interfaces. In 2023 IEEE International Conference on Metaverse Computing, Networking and Applications, 134-138.
[22]. Limchesing, T., Chua, A., Shi, C., Baldovino, R., et, al. (2021). A review on recent applications of EEG-based BCI in wheelchairs and other assistive devices. In 2021 IEEE 13th International Conference on Humanoid, Nanotechnology, Information Technology, Communication and Control, Environment, and Management, 1-6.
[23]. Karikari, E., & Koshechkin, K. A. (2023). Review on brain-computer interface technologies in healthcare. Biophysical Reviews, 15(5), 1351-1358.
[24]. Patel, N., Verma, J., & Jain, S. (2023). Emerging Applications of Brain Computer Interfaces: A Comprehensive Review and Future Perspectives. In 2023 IEEE 11th Region 10 Humanitarian Technology Conference, 312-317.
Cite this article
Xiong,M. (2024). Brain-computer interface applications in the aging population with Alzheimer’s and Parkinson’s disease. Applied and Computational Engineering,81,47-55.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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