Principle and Application of Lipid Nanoparticles in Cosmetics

Research Article
Open access

Principle and Application of Lipid Nanoparticles in Cosmetics

Linwen Yu 1*
  • 1 Northwest Normal University    
  • *corresponding author 202031805624@nwnu.edu.cn
Published on 7 November 2023 | https://doi.org/10.54254/2755-2721/24/20230714
ACE Vol.24
ISSN (Print): 2755-273X
ISSN (Online): 2755-2721
ISBN (Print): 978-1-83558-069-1
ISBN (Online): 978-1-83558-070-7

Abstract

Lipid nanoparticles (LNs) are colloidal particles having a biocompatible lipid matrix and nanoparticle (NP) sizes between 100 nm and 400 nm. They are called "nanosafe" carriers and show outstanding tolerability. Solid lipid nanoparticles use lipid as the skeleton material which has a high melting point. SLNs have the characteristics of high physical stability, relatively less drug leakage and good slow release, low toxicity and easy to mass production. The structure of the solid particle matrix allows solid lipid nanoparticles (SLNs) to be distinguished from nanostructured lipid carriers (NLCs). NLC is prepared by mixing liquid lipids and solid lipids. NLC improves the solubility of the active substance, improves the release ability of the substance, and also prolongs the storage life of the active substance in the carrier. Plenty of characteristics for skin application of pharmaceuticals and cosmetics are displayed by SLNs and NLC, such as drug targeting, regulated release of active ingredients, occlusion properties, and related enhancements to penetration and skin hydration. This review focuses on the characteristic of SLNs and NLCS, analyzing their advantages and disadvantages and lipid nanoparticles application in cosmetics are described in detail.

Keywords:

lipid nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, penetration, application

Yu,L. (2023). Principle and Application of Lipid Nanoparticles in Cosmetics. Applied and Computational Engineering,24,231-236.
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References

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[14]. Hommoss A, Souto E B, and Müller R H, 2005 Annual Meeting and Exposition #M1238 6–10.

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[18]. Lambers H, Piessens S, Bloem A, Pronk H, and Finkel P, 2006 Int. J. Cosmet. Sci. 28 359–370.

[19]. Li M. 2015 Study on encapsulation and stability of nature active products. Beijing University of Chemical Technology.

[20]. Mitri K, Shegokar R, Gohla S, et al. 2011 International Journal of Pharmaceutics,414 267-275.

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[22]. Yoon G, Park J W, Yoon I S. 2013 J Pharm Investig. 43 353–362.


Cite this article

Yu,L. (2023). Principle and Application of Lipid Nanoparticles in Cosmetics. Applied and Computational Engineering,24,231-236.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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About volume

Volume title: Proceedings of the 2023 International Conference on Functional Materials and Civil Engineering

ISBN:978-1-83558-069-1(Print) / 978-1-83558-070-7(Online)
Editor:Bhupesh Kumar
Conference website: https://www.conffmce.org/
Conference date: 26 August 2023
Series: Applied and Computational Engineering
Volume number: Vol.24
ISSN:2755-2721(Print) / 2755-273X(Online)

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References

[1]. Üner M, Yener G, 2007 Int. J. Nanomed. 2 289.

[2]. Puri A, Loomis K, Smith B, et al. 2009 Crit. Rev. Ther. Drug Carrier Syst. 26 523.

[3]. Crosera M, Bovenzi M, Maina G, et al. 2009 Int. Arch.Occup. Environ. Health 82 1043–1055.

[4]. Cevc G, Vierl U, 2021 J. Controlled Release 141 277–299.

[5]. Kakadia P G, Conway B R, 2015 Am. J. Pharmacol. Sci. 2 1–7.

[6]. Purohit D K, 2016 Asian J.Pharm. (AJP) 10 1.

[7]. Madani S Y, Mandel A.M. Seifalian, 2013 Nano Rev. 4 15-21.

[8]. Castro G A, Orefice R L, Vilela J M, Andrade M S and Ferreira L A,2007 acne. J. Microencapsul. 24 395–407.

[9]. Parhi R, Suresh P, 2010 J. Chem. Pharm. Res. 2 211–227.

[10]. Wissing, S. A. and Muller, R. H. 2003 International Journal of Pharmaceutics 254 65– 68.

[11]. Sivaramakrishnan R, et al., 2004 J. Control. Release 97 493–502.

[12]. Liu X. 2016 Preparation and characterization of the nanostructured lipid carriers loaded UVA/UVB sunscreens, Shanghai Institute of Technology.

[13]. Ling H, Zheng C, Mao T, et al. 2018 Journal of Chemical Engineering of Chinese Universities, 32 377-385.

[14]. Hommoss A, Souto E B, and Müller R H, 2005 Annual Meeting and Exposition #M1238 6–10.

[15]. Wissing SA, Mäder K and Müller R H, 2000 In Proc. Int. Symp. Control Rel Bioact Mater 27, 311–312.

[16]. Wissing S A, and Muller R H, 2003 Eur. J. Pharm. Biopharm. 56 67–72.

[17]. Villalobos-Hernandez J R, Muller-Goymann C C, 2005 Eur. J. Pharm. Biopharm. 60 113–122.

[18]. Lambers H, Piessens S, Bloem A, Pronk H, and Finkel P, 2006 Int. J. Cosmet. Sci. 28 359–370.

[19]. Li M. 2015 Study on encapsulation and stability of nature active products. Beijing University of Chemical Technology.

[20]. Mitri K, Shegokar R, Gohla S, et al. 2011 International Journal of Pharmaceutics,414 267-275.

[21]. Fatime Pinto, Drangana P C, de Barros, et al. 2018 Industrial Crops&Products, 118 149-159.

[22]. Yoon G, Park J W, Yoon I S. 2013 J Pharm Investig. 43 353–362.