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Published on 21 July 2023
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Hu,B.;Bao,Z.;Jiang,R.;Zhang,Y. (2023). Introduction to organic synthetic method retrosynthetic analysis. Applied and Computational Engineering,7,546-561.
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Introduction to organic synthetic method retrosynthetic analysis

Bohan Hu *,1, Zitong Bao 2, Rixing Jiang 3, Yuhan Zhang 4
  • 1 Shenzhen College of International Education
  • 2 Merchiston International School
  • 3 Shuren School of Yangzhou High School Education Group
  • 4 Dipont Huayao Collegiate School Kunshan

* Author to whom correspondence should be addressed.

https://doi.org/10.54254/2755-2721/7/20230482

Abstract

Retrosynthesis is a method that uses the target molecule, which is a product, to predict the reactant, which is useful in organic synthesis and also a reverse way of synthesis. This paper introduces retrosynthetic analysis of organic compounds and helps new learners to have a brief understanding of what retrosynthetic analysis is, the disconnection methods, guidelines and real world applications of retrosynthesis based on an easy and basic explanation. Understanding retrosynthesis is helpful in industrial uses and manufacturing, as it can figure out the most efficient strategy by comparing different synthetic routine.

Keywords

disconnection method, functional group manipulation, real life examples

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Cite this article

Hu,B.;Bao,Z.;Jiang,R.;Zhang,Y. (2023). Introduction to organic synthetic method retrosynthetic analysis. Applied and Computational Engineering,7,546-561.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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About volume

Volume title: Proceedings of the 3rd International Conference on Materials Chemistry and Environmental Engineering (CONF-MCEE 2023), Part II

Conference website: https://www.confmcee.org/
ISBN:978-1-915371-61-4(Print) / 978-1-915371-62-1(Online)
Conference date: 18 March 2023
Editor:Ioannis Spanopoulos, Niaz Ahmed, Sajjad Seifi Mofarah
Series: Applied and Computational Engineering
Volume number: Vol.7
ISSN:2755-2721(Print) / 2755-273X(Online)

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