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The impact of comprehensive treatment on pregnancy outcomes in patients with polycystic ovary syndrome
- 1 Anhui Medical University
* Author to whom correspondence should be addressed.
Abstract
This study focuses on the impact of comprehensive treatment on pregnancy outcomes in patients with polycystic ovary syndrome (PCOS). In this research, 60 PCOS patients admitted to our hospital between January 2022 and April 2023 were selected and randomly divided into two groups. The control group (n=30) received conventional Western medical treatment, while the observation group (n=30) received integrated traditional Chinese and Western medicine treatment. The two groups were compared in terms of sex hormone levels, endometrial receptivity indices, pregnancy outcomes, incidence of adverse reactions, overall treatment efficacy, and Traditional Chinese Medicine (TCM) syndrome scores. The study found that before treatment, there were no significant differences between the two groups in terms of sex hormone levels, endometrial receptivity indices, and TCM syndrome scores (P>0.05). After treatment, the observation group showed significantly better results than the control group in these indices (P<0.05). The pregnancy outcomes in the observation group were superior to those in the control group (P<0.05), the incidence of adverse reactions was lower in the observation group (P<0.05), and the overall clinical efficacy was higher in the observation group (P>0.05). In conclusion, comprehensive treatment combining traditional Chinese and Western medicine can improve pregnancy outcomes in PCOS patients and is worthy of promotion.
Keywords
polycystic ovary syndrome, integrated traditional Chinese and western medicine treatment, pregnancy outcomes, sex hormones, endometrial receptivity
[1]. Wu, J. M., Zhuo, Y. Y., Tang, M., et al. (2021). Effects of Tiao Ren Tong Du acupuncture on pregnancy outcomes after in vitro fertilization-embryo transfer in patients with polycystic ovary syndrome infertility. Shanghai Journal of Acupuncture and Moxibustion, 40(5), 565-570.
[2]. Zhu, S. F., Liu, H., He, J. Y., et al. (2020). Study on the therapeutic effects of two different treatment schemes on 70 patients with polycystic ovary syndrome infertility. Journal of Inner Mongolia Medical University, 42(3), 314-317.
[3]. Ye J, Su K L, Xu Y H, et al.Effect of Salivary Antimicrobial Factors on Microbial Composition of Tongue Coating in Patients with Coronary Heart Disease with Phlegm-Stasis Syndrome[J].World Journal of Traditional Chinese Medicine, 2022(1):123-130.
[4]. Peng, X. P., Li, Q. Y., Liao, W. (2020). Study on the effects and partial mechanisms of Cangfu Daotan Pill on pregnancy outcomes in polycystic ovary syndrome. World Chinese Medicine, 15(18), 2767-2771.
[5]. Cho Y S , Bae K S , Choi S C ,et al.Population Pharmacokinetic and Pharmacodynamic Analysis of Polmacoxib in Healthy Volunteers and Patients With Osteoarthritis[J].Clinical therapeutics, 2022, 44(1):67-80.
[6]. Liu, X. J., Liu, W. Z., Zhang, J. P. (2023). Analysis of the effects of clomiphene citrate combined with estradiol valerate tablets on endometrial ICAM-1 gene, thickness, and pregnancy outcomes in polycystic ovary syndrome. Experimental and Laboratory Medicine, (4), 476-478, 482.
[7]. Zheng, J., Dai, X. Y. (2020). Effects of tamoxifen on sex hormone levels and pregnancy outcomes in patients with polycystic ovary syndrome infertility. Contemporary Medicine, 26(33), 65-67.
[8]. Bi, F. X., Wu, L. L., Zhang, H., et al. (2022). Effects of Hashi's ovulation-promoting formula on endometrial receptivity and pregnancy outcomes in patients with polycystic ovary syndrome. Liaoning Journal of Traditional Chinese Medicine, 49(4), 83-87.
[9]. Raperport C , Chronopoulou E , Homburg R .Effects of metformin treatment on pregnancy outcomes in patients with polycystic ovary syndrome[J].Expert review of endocrinology & metabolism, 2021, 16(2):37-47.
[10]. Jia-Man W U , Yan N , Yang-Yang Y E ,et al.Effects of Acupuncture on Endometrium and Pregnancy Outcomes in Patients with Polycystic Ovarian Syndrome Undergoing in vitro Fertilization-Embryo Transfer:A Randomized Clinical Trial[J].Chinese Journal of Integrative Medicine, 2022(8):736-742.
[11]. Wu J M , Ning Y , Ye Y Y ,et al.Effects of Acupuncture on Endometrium and Pregnancy Outcomes in Patients with Polycystic Ovarian Syndrome Undergoing in vitro Fertilization-Embryo Transfer: A Randomized Clinical Trial[J].Chinese journal of integrative medicine, 2022, 28(8):736-742.
[12]. Bi H , Aldakheel F M , Aloahd M S .The effect of prednisolone on endometrial VGEF concentrations, Gene polymorphisms and pregnancy outcome in women with polycystic ovary syndrome: A retrospective cohort study[J].Journal of Reproductive Immunology, 2020, 137:103081.
[13]. Vonica C L , Farcas A D , Roman G ,et al.Metabolomic biomarkers of polycystic ovary syndrome related-obesity: a review of the literature[J].Revista Romana de Medicina de Laborator, 2020, 28(3):241-255.
[14]. Chang C , Chang S , Poles J ,et al.The Impact of Bariatric Surgery Compared to Metformin Therapy on Pregnancy Outcomes in Patients with Polycystic Ovarian Syndrome: a Systematic Review and Meta-analysis[J].Journal of Gastrointestinal Surgery, 2021,25(2):378-386.
Cite this article
Wang,Q. (2024). The impact of comprehensive treatment on pregnancy outcomes in patients with polycystic ovary syndrome. Journal of Clinical Technology and Theory,1,23-27.
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The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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