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Effects of Xuefu Zhuyu Decoction on cognitive function in patients with depression
- 1 Second Affiliated Hospital of Nanjing University of Chinese Medicine; Jiangsu Provincial Second Chinese Medicine Hospital; Second Clinical Medical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210000, China
- 2 Second Affiliated Hospital of Nanjing University of Chinese Medicine; Jiangsu Provincial Second Chinese Medicine Hospital; Second Clinical Medical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210000, China
- 3 Second Affiliated Hospital of Nanjing University of Chinese Medicine; Jiangsu Provincial Second Chinese Medicine Hospital; Second Clinical Medical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210000, China
- 4 Second Affiliated Hospital of Nanjing University of Chinese Medicine; Jiangsu Provincial Second Chinese Medicine Hospital; Second Clinical Medical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210000, China
* Author to whom correspondence should be addressed.
Abstract
Depression is a common, serious, and recurrent mental disorder that is closely associated with decreased quality of life, increased medical morbidity, and higher mortality rates. Currently, over 300 million people worldwide are affected by depression. According to reports from the World Health Organization (WHO), psychological disorders account for 12% of the global disease burden, and 46% of all illnesses are directly related to depression. WHO experts have warned that, if this trend continues, by 2030 the number of patients with depression will exceed the total number of patients with all cardiovascular diseases, making depression the leading cause of disability worldwide. It has thus become a major global public health concern. Xuefu Zhuyu Decoction, originally recorded in Correction of Errors in Medical Classics by Qing dynasty physician Wang Qingren, is known for its functions of promoting blood circulation, removing blood stasis, regulating qi, and relieving pain. It is now widely used in clinical practice for various conditions characterized by qi stagnation and blood stasis, with notable efficacy. This paper systematically elaborates on the therapeutic effects and mechanisms of Xuefu Zhuyu Decoction in treating depression accompanied by cognitive dysfunction.
Keywords
Xuefu Zhuyu Decoction, depression, cognitive impairment
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Cite this article
Liu,C.;Sheng,L.;Gong,Y.;Wu,K. (2025). Effects of Xuefu Zhuyu Decoction on cognitive function in patients with depression. Journal of Clinical Technology and Theory,3(1),61-65.
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