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Investigation of Matrix Effect in the Determination of Bisphenols in Aquatic Products by Liquid Chromatography-Mass Spectrometry
- 1 Xi’an Jiaotong-Liverpool University, Suzhou, China
* Author to whom correspondence should be addressed.
Abstract
In this study, techniques such as liquid chromatography-ultraviolet photometric de- tector and evaporative light scattering detector were used to search for substances in the matrix that produced matrix effects when LC-MS was used to determine bisphenol compounds in aquatic products. This study provides new insights for researchers dealing with matrix effect problems. Bisphenols are introduced, with a focus on BPA and BPS. LC-MS is a commonly used method for the determination of bisphenols, but it is often affected by matrix effects, primarily due to phospholipids present in aquatic products. To confirm this, a chromatographic method was established to identify substances in the matrix that may co-elute with BPs. Phospholipids were confirmed as significant contrib- utors to matrix effects. Finally, commonly used methods to eliminate matrix effects are summarized
Keywords
bisphenol compounds, matrix effect, LC-MS, aquatic products
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Cite this article
Abduhabar,A. (2025). Investigation of Matrix Effect in the Determination of Bisphenols in Aquatic Products by Liquid Chromatography-Mass Spectrometry. Applied and Computational Engineering,124,15-19.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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Volume title: Proceedings of the 5th International Conference on Materials Chemistry and Environmental Engineering
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