
Gene expression controlled by stem cells and its relationship with cancer
- 1 The Chinese University of Hongkong
* Author to whom correspondence should be addressed.
Abstract
The stem cell is one type of cell that has a strong ability to differentiate and self-renew. It plays a vital role in the cell cycle and gene regulation. Also, due to its unique ability to self-regenerate, stem cells have the potential to produce medicines. In this article, it will talk about stem cells controlling the gene expression mechanism and focus on recent research that has revealed a relationship between stem cells and tumor cells, indicating a potential way to treat cancer, and cancer stem cell theory showing the similarity between the stem cell and the cancer cell at the starting point which gives birth to the tumor such theory gives a new understanding towards the existence of cancer. Another important subject about stem cell is mesenchymal stem cells (MSC), which is one type of stem cell that is focused and well-studied due to its owning of enormous clinical application potential.
Keywords
stem cell, cancer stem cell, self-renewal
[1]. Korinek V, Barker N, Moerer P, et al. 1998 Nature genetics 19(4) 379-383
[2]. George A A, Franklin J, Kerkof K, et al. 2001 Blood, The Journal of the American Society of Hematology 97(12) 3925-3930
[3]. Clayton E, Doupé D P, Klein A M, et al. 2007 Nature 446(7132) 185-189
[4]. Sato T, Van Es J H, Snippert H J, et al. 2011 Nature 469(7330) 415-418
[5]. Quintana E, Shackleton M, Sabel M S, et al. 2008 Nature 456(7222) 593-598
[6]. Gupta P B, Fillmore C M, Jiang G, et al. 2011 Cell 146(4) 633-644
[7]. Cano A, Pérez-Moreno M A, Rodrigo I, et al. 2000 Nature cell biology 2(2) 76-83
[8]. Suda T, Takubo K, Semenza G L. 2011 Cell stem cell 9(4) 298-310
[9]. Rodríguez-Fuentes D E, Fernández-Garza L E, Samia-Meza J A, et al. 2021 Archives of medical research 52(1) 93-101
[10]. Sheng G. 2015 BMC developmental biology 15 1-8
Cite this article
Hu,Y. (2024). Gene expression controlled by stem cells and its relationship with cancer. Theoretical and Natural Science,32,52-56.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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Volume title: Proceedings of the 2nd International Conference on Modern Medicine and Global Health
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