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The Therapeutic Value of Tetrodotoxin
- 1 Beijing Twenty-first century International School
- 2 Shanghai Xiwai International School, SISU
* Author to whom correspondence should be addressed.
Abstract
Tetrodotoxin is a very important toxin to study because there are many cases of intoxication of tetrodotoxin. In this review, we will illustrate the therapeutic value of tetrodotoxin by explaining the mechanism of tetrodotoxin, the importance of tetrodotoxin as a pain treatment, and some clinical evidence. Tetrodotoxin can prevent the neurons from traveling through the voltage-gated sodium ion channel and stop the transmission of the neurons and stimuli, which makes tetrodotoxin able to treat several types of pain such as visceral pain and cancer pain. By blocking the neurons and stimuli in the body, the feeling of pain will not occur in the body. The two clinical examples show that Tetrodotoxin is effective in treating pain but not as effective as morphine. Therefore, the use of tetrodotoxin to treat pain may reduce the use of morphine.
Keywords
tetrodotoxin, toxicology, therapy, pain.
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Cite this article
Wang,Z.;Zheng,H. (2023). The Therapeutic Value of Tetrodotoxin. Theoretical and Natural Science,4,673-677.
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Volume title: Proceedings of the 2nd International Conference on Biological Engineering and Medical Science (ICBioMed 2022), Part II
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