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Research on the preparation of water-soluble plant sterol derivatives
- 1 Beijing University of Chemical Technology
- 2 Beijing University of Chemical Technology
- 3 Beijing University of Chemical Technology
* Author to whom correspondence should be addressed.
Abstract
Phytosterol is a kind of natural bioactive substance that has the functions of lipid-lowering, anti-oxidation, and anti-tumor. However, due to its water solubility, poor dispersion, and very low absorption efficiency, natural plant sterols have severely restricted their application in food processing. This study aims to improve the water solubility of phytosterols in food by modifying them, to expand the possibility of their application in food, medicine, and cosmetics. Phytosterol derivatives with good water solubility were successfully synthesized by using acid-functionalized ionic liquid and PEG with different molecular weights as catalysts and hydrophilic modifiers. The high-purity product was obtained by chemical reaction, separation, and purification. The structure of the product was characterized by thin-layer chromatography, high-performance liquid chromatography, and infrared spectroscopy. The results showed that the phytosterol derivatives prepared by optimized synthesis conditions and purification methods had good water solubility, which provided a new possibility for its application in drug development, food additives, and cosmetics. However, there are still some challenges and problems in the research, and it is necessary to further optimize the experimental conditions and the biological activity of the research products to promote the in-depth development of the field. Through this study, we have made a preliminary exploration for the development of related fields and provided a reference for future research.
Keywords
Plant sterols, Water solubility, Preparation of derivatives 1. Introduction
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Cite this article
Xiang,Q.;Mo,J.;Chen,B. (2024). Research on the preparation of water-soluble plant sterol derivatives. Theoretical and Natural Science,35,189-197.
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The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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Volume title: Proceedings of the 2nd International Conference on Modern Medicine and Global Health
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