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Explore the impact of the use of two different odors in training on the behavioural and neuroanatomical of reversing intergenerational stress in mice
- 1 Beijing University of Aeronautics and Astronautic
- 2 Hurtwood House
- 3 Yuen Long Merchants Association Secondary School
- 4 Zhengzhou University
* Author to whom correspondence should be addressed.
Abstract
Current research has indicated that stress from relatives affects not only relatives but also their offspring, and that therefore, effective intergenerational genetics to prevent stress would be beneficial to public health, while odor-based fear adjustment provides a way to address the problem. So our research is aimed at examining the intergenerational genetic trauma and stress. We adjusted the odor fear of F0 mice before they were conceived, and we trained F0 mouse with two different odors (cumin and cinnamon). We expose mice in a particular group of experiments to a specific odor (cumin or cinnamon) and train them to associate the odor with current stimulation (conditioning). At the same time, we will also help mice to eliminate their fear of extinction in a way that shows only the smell after the conditioning training of other specific groups of mice. We then performed behavioral and neurosynthesis tests on F0 offspring of F1 mice under different conditions, with specific smell and no specific odor (two of which were used to train F0 mice), and tested the egg cells of offsprings of females. We hope to use the findings to further explain the previously undetected methods of intergenerational stress genetic reversal, further explaining how environmental information, as well as multiple environmental data, are transgenetic at the behavioral, neuro-anatomical and epigenetic levels. This will further reveal the potential for extinction training to be applied to family training to reverse the impact of family stress sources on offspring.
Keywords
Behavioral sensitivity, Neuroanatomical test, Extinction training, Olfaction, Olfactory sensory neurons, Ovum
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Cite this article
Zhu,F.;Gu,J.;Lin,L.;Zhang,W. (2024). Explore the impact of the use of two different odors in training on the behavioural and neuroanatomical of reversing intergenerational stress in mice. Theoretical and Natural Science,45,113-121.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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Volume title: Proceedings of the 2nd International Conference on Modern Medicine and Global Health
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