Compare the open-looped DBS and closed-looped DBS on treatment on tourette syndrome
- 1 International Department, Chengdu Foreign Language School, No.33 Baicao Road, Cooperation Street, Chengdu, China
* Author to whom correspondence should be addressed.
Abstract
Abstract. Tourette Syndrome (TS), a complex neurodevelopmental disorder featured by persistent motor and vocal tics, has seen Deep Brain Stimulation (DBS) emerge as an efficacious treatment option for refractory cases. This study aims to systematically review and compare the roles of open-loop and closed-loop DBS modalities in treating TS, to elucidate their respective strengths, priorities, and clinical outcomes. Through a comprehensive literature review and data analysis, this paper delves into the mechanisms, technical advantages, and effectiveness of both DBS paradigms in managing TS symptoms, mitigating comorbidities, and enhancing quality of life. Furthermore, the disparities in safety, tolerability, long-term efficacy, and the influence of patient-specific requirements on therapeutic strategy selection are evaluated. Besides, this paper also culminates with a summary and outlook, advocating for ongoing exploration to refine closed-loop DBS pathways and concurrent appraisal of open-loop DBS within specific patient cohorts, thereby advancing the precision and personalization of TS therapy.
Keywords
Keywords: Tourette syndrome, deep brain stimulation, open-loop DBS, closed-loop DBS, neurodevelopmental disorders.
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Cite this article
Wang,M. (2024).Compare the open-looped DBS and closed-looped DBS on treatment on tourette syndrome.Theoretical and Natural Science,64,33-39.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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