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Review on Intestinal Stem Cell
- 1 School of Bioinformatics, Zhejiang University, Zhejiang, China
* Author to whom correspondence should be addressed.
Abstract
The intestine performs the functions of absorption and protection. Located in the intestine, the intestinal stem cells play an important role in sustaining the intestinal homeostasis. The niche environment affects the intestinal stem cells functions via signaling, structural, and immune pathways. Active intestinal stem cells can differentiate into other intestinal cells and replenish them. This process is regulated by various signaling pathways, including Wnt, BMP, EGF and so on. In addition, other impact factors like aging and microbiota may also influence the intestinal homeostasis through affecting intestinal stem cells. Colorectal cancer, originating from abnormal intestinal stem, may be treated by multiple therapies
Keywords
Intestinal stem cell, homeostasis, CLC
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Cite this article
Chen,R. (2025). Review on Intestinal Stem Cell. Theoretical and Natural Science,68,159-163.
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Volume title: Proceedings of the 3rd International Conference on Modern Medicine and Global Health
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