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Blood-brain barrier on-a-chip and its application
- 1 University of Cambridge
* Author to whom correspondence should be addressed.
Abstract
In the past five years, the organ-on-a-chip technology developed quickly and provided a novel platform for in vitro modelling and experimental testing. Blood-brain barrier (BBB) is an important barrier separating the brain from the rest of the body, thereby protecting the brain from toxins. It is important to study the BBB in terms of its permeability to various molecules, not only identifying potential toxins that might harm the brain, but also to design administration routes for drugs targeting the central nervous system (CNS). This review will summarize various recent designs of the BBB chips and their pros and cons, as well as the future directions for the organ-on-chip technology.
Keywords
Blood-Brain Barrier, Organ-On-A-Chip, In Vitro Modelling, Neurological Diseases, Drug Delivery
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Cite this article
Zhou,S. (2023). Blood-brain barrier on-a-chip and its application. Theoretical and Natural Science,8,284-289.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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Volume title: Proceedings of the 2nd International Conference on Modern Medicine and Global Health
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