
Biomedical applications of fluorescent biosensors
- 1 Clinical Engineering Technology, Shanghai University of Medicine & Health Sciences, Shanghai, China
* Author to whom correspondence should be addressed.
Abstract
This study aims to systematically summarize the development history of fluorescent biosensors and their applications in biomedicine, and propose optimization strategies to promote the development of fluorescent biosensor technology according to the current challenges. This paper collects the literature of relevant research at home and abroad, and organizes and analyzes the basic principles, development history and biomedical applications of fluorescent biosensors. In addition, in view of the problems existing in fluorescent biosensors, some potential optimization strategies are proposed. After sorting out and analyzing the development history of fluorescent biosensors, it can be seen that the technology of fluorescent biosensors has made significant progress. In the field of biomedicine, fluorescent biosensors have been successfully applied to biomolecular detection, disease diagnosis and drug screening, showing great application potential. However, current fluorescent biosensors still face some challenges, such as light stability and sensitivity, which need to be further optimized. In summary, the application of fluorescent biosensors in biomedicine has broad prospects, but some technical challenges still need to be overcome.
Keywords
Fluorescent Biosensors, Development, Biomedical Applications
[1]. Zipfel W R, Williams R M, Christie R, Nikitin A Y, Hyman B T and Webb W W Proc. Natl. Acad. Sci. U.S.A. 2003 100 7075-7080
[2]. Wall K P, Dillon R and Knowles M K Biochem. Mol. Biol. Educ. 2015 43 52-59
[3]. Gaviria-Arroyave M I, Cano J B and Peñuela G A Talanta Open 2020 2 100006
[4]. Hu S, Liu J, Wang Y, Liang Z, Hu B, Xie J, Wong W-L, Wong K-Y, Qiu B and Peng W Sensors Actuators B: Chem. 2023 380 133379
[5]. Hejji L, Azzouz A, Kukkar D and Kim K-H TrAC, Trends Anal. Chem. 2023 166 117194
[6]. Kairdolf B A, Smith A M, Stokes T H, Wang M D, Young A N and Nie S Annu. Rev. Anal. Chem. (Palo Alto Calif.) 2013 6 143-162
[7]. Jia X and Zhu L Acc. Chem. Res. 2023 56 655-666
[8]. Kunc F, Moore C J, Sully R E, Hall A J and Gubala V Langmuir 2019 35 4909-4917
[9]. Schaue D and Mcbride W Front. Oncol. 2012 2 119
[10]. Pan Y and Zhang L Arch. Comput. Methods Eng. 2023 30 1081-1110
Cite this article
Zhou,Y. (2023). Biomedical applications of fluorescent biosensors. Theoretical and Natural Science,23,265-271.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
Disclaimer/Publisher's Note
The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of EWA Publishing and/or the editor(s). EWA Publishing and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.
About volume
Volume title: Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
© 2024 by the author(s). Licensee EWA Publishing, Oxford, UK. This article is an open access article distributed under the terms and
conditions of the Creative Commons Attribution (CC BY) license. Authors who
publish this series agree to the following terms:
1. Authors retain copyright and grant the series right of first publication with the work simultaneously licensed under a Creative Commons
Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this
series.
2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the series's published
version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial
publication in this series.
3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and
during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See
Open access policy for details).