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Published on 20 December 2023
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Geng,J. (2023).Research on the application of microRNA in hepatocellular carcinoma.Theoretical and Natural Science,24,40-44.
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Research on the application of microRNA in hepatocellular carcinoma

Jinrong Geng *,1,
  • 1 Shenyang Pharmaceutical University

* Author to whom correspondence should be addressed.

https://doi.org/10.54254/2753-8818/24/20231092

Abstract

The digestive tract frequently develops the malignant tumor known as hepatocellular carcinoma (HCC). A variety of liver diseases can develop into HCC and therefore a therapeutic approach is required. Extracellular vesicles known as exosomes are released by a number of cells and contain a wide range of active substances, including lipids, proteins, RNA, and DNA. microRNA is a type of RNA that accelerates apoptosis by participating in the regulation of downstream gene translation. Studies have shown that exosomal micrornas regulate HCC. Exosomal microRNAs have been proven in studies which regulate HCC. Exosomal micrornas may therefore be particular biomarkers for HCC metastases and early diagnosis as well as possible therapeutic targets. The utilization of exosomal micrornas in HCC is employed as biomarkers for early diagnosis and may trigger cancer cell apoptosis through the PI3K-AKT channel or MAPKs/ERK channel to produce therapeutic effects. Exosomal micrornas are briefly detailed in this paper.

Keywords

microRNAs, HCC, exosomes, application

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Cite this article

Geng,J. (2023).Research on the application of microRNA in hepatocellular carcinoma.Theoretical and Natural Science,24,40-44.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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About volume

Volume title: Proceedings of the 3rd International Conference on Biological Engineering and Medical Science

Conference website: https://www.icbiomed.org/
ISBN:978-1-83558-221-3(Print) / 978-1-83558-222-0(Online)
Conference date: 2 September 2023
Editor:Alan Wang
Series: Theoretical and Natural Science
Volume number: Vol.24
ISSN:2753-8818(Print) / 2753-8826(Online)

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