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DNA Data Storage: The Fusion of Digital and Biological Information
- 1 School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, China
* Author to whom correspondence should be addressed.
Abstract
With the development of Internet technology, human information data grows by a huge amount. Traditional data storage media are no longer suitable for large amounts of data storage due to their inherent shortcomings, such as high power consumption, large physical size, and short storage life. DNA information storage, on the other hand, can overcome these shortcomings to a certain extent. This paper introduces the process and mechanism of DNA storage, such as the DNA synthesis method, DNA coding, DNA preservation and sequencing, the history of DNA storage, its defects, and shortcomings. This article introduces the principles and mechanisms of DNA storage, including DNA synthesis method, data storage, and DNA preservation, as well as the history of DNA storage and its shortcomings and prospects for improvement, using the comparison of traditional storage methods and DNA storage methods as an import cut.
Keywords
DNA synthesis, data encoding, DNA preservation, DNA storage history
[1]. Y. Yang and C.H. Fan, Synthetic biology. 2(3): p. 305-308 (2021).
[2]. CHEN, W., et al., SCIENTIA SINICA Vitae. 50(1674-7232): p. 81 (2020).
[3]. D.M. Chen, et al., Synthetic biology. 2(3): p. 399-411 (2021).
[4]. Kosuri, S. and G.M. Church, Nature Methods. 11(5): p. 499-507 (2014).
[5]. Saini, N., et al., Nature. 502(7471): p. 389-392 (2013).
[6]. Song, X.-P., et al., Chemistry & biodiversity. 9(12): p. 2685-2700 (2012).
[7]. T.Y. Zhou, Y. Luo, and X.Y. Jiang, Synthetic biology. 2(3): p. 371-383 (2021).
[8]. Lim, C.K., et al., Trends Biotechnol. 39(10): p. 990-1003 (2021).
[9]. Grass, R.N., et al., Angewandte Chemie International Edition. 54(8): p. 2552-2555 (2015).
[10]. Erlich, Y. and D. Zielinski, Science. 355(6328): p. 950-954 (2017).
[11]. Ausländer, S. and M. Fussenegger, Science. 346(6211): p. 813-814 (2014).
[12]. Farzadfard, F. and T.K. Lu, Science. 361(6405): p. 870-875 (2018).
[13]. Organick, L., et al., Nature Biotechnology. 36(3): p. 242-248 (2018).
[14]. Yachie, N., et al., Biotechnol Prog. 23(2): p. 501-5 (2007).
[15]. Tabatabaei Yazdi, S.M.H., et al., Scientific Reports. 5(1): p. 14138 (2015).
[16]. Sheth, R.U. and H.H. Wang, Nat Rev Genet. 19(11): p. 718-732 (2018).
[17]. Bibikova, M., et al., Science. 300(5620): p. 764 (2003).
[18]. Wirth, D., et al., Curr Opin Biotechnol. 18(5): p. 411-9 (2007).
[19]. Marraffini, L.A., Nature. 526(7571): p. 55-61 (2015).
[20]. Xie, Z.X., et al., G3 (Bethesda). 8(1): p. 173-183 (2018).
[21]. Kalhor, R., P. Mali, and G.M. Church, Nature Methods. 14(2): p. 195-200 (2017).
[22]. M.Y. Gao, et al., Synthetic biology. 2(3): p. 384-398 (2021).
[23]. Baum, E.B., Science. 268(5210): p. 583-585 (1995).
[24]. Davis, J., Art Journal. 55(1): p. 70-74 (1996).
[25]. Clelland, C.T., V. Risca, and C. Bancroft, Nature. 399(6736): p. 533-534 (1999).
[26]. Ailenberg, M. and O. Rotstein, Biotechniques. 47(3): p. 747-54 (2009).
[27]. Bancroft, C., et al., Science. 293(5536): p. 1763-1765 (2001).
[28]. Gibson, D.G., et al., Science. 329(5987): p. 52-6 (2010).
[29]. Wong, P.C., K.K. Wong, and H. Foote, Commun. ACM. 46: p. 95-98 (2003).
[30]. Church, G.M., Y. Gao, and S. Kosuri, Science. 337(6102): p. 1628-1628 (2012).
[31]. Blawat, M., et al., Procedia Computer Science. 80: p. 1011-1022 (2016).
[32]. Shipman, S.L., et al., Nature. 547(7663): p. 345-349 (2017).
[33]. Hao, M., et al., Commun Biol. 3(1): p. 416 (2020).
[34]. Goldman, N., et al., Nature. 494(7435): p. 77-80 (2013).
[35]. Zhirnov, V.V. and D. Rasic, 2018 Semiconductor Synthetic Biology Roadmap. 2018.
[36]. L. Qian, et al., Synthetic biology. 2(3): p. 303-304 (2021).
Cite this article
Li,X. (2023). DNA Data Storage: The Fusion of Digital and Biological Information. Theoretical and Natural Science,4,26-31.
Data availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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Volume title: Proceedings of the 2nd International Conference on Biological Engineering and Medical Science (ICBioMed 2022), Part II
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