Current Situation and the Challenge of Eliminating Hepatitis B in Sub-Saharan Africa

Research Article
Open access

Current Situation and the Challenge of Eliminating Hepatitis B in Sub-Saharan Africa

Minxing Li 1 , Aiyue Ou 2 , Zhuoran Xiao 3
  • 1 School of Nursing, Queensland University of Technology, Brisbane, Queensland State, Australia    
  • 2 School of Basic Medical Sciences, Southern Medical University, Guangdong, 510515, China    
  • 3 School of Public Health, Capital Medical University, Beijing, 100069, China    
  • *corresponding author
Published on 28 April 2023 | https://doi.org/10.54254/2753-8818/3/20220293
TNS Vol.3
ISSN (Print): 2753-8826
ISSN (Online): 2753-8818
ISBN (Print): 978-1-915371-25-6
ISBN (Online): 978-1-915371-26-3

Abstract

Chronic hepatitis B (CHB) belongs to chronic inflammatory disease. It is primarily transmitted through blood, mother to child, and sexual contact. In clinical practice, it is necessary to improve the examination as soon as possible. Only by early treatment can people delay and control the development of the disease and stabilize the disease. Otherwise, it will cause cirrhosis and lead to complications, such as ascites, bleeding, liver cancer, and so on. Antiviral therapy is the first choice for chronic hepatitis B virus infection. There are many drugs related to antiviral treatment in clinics, and different drugs have different effects. Vaccination can reduce the occurrence of diseases to a certain extent. However, despite hepatitis B having very effective vaccinations and excellent vaccinations available, there are still lots of patients that with the chronic hepatitis B in the sub-Saharan Africa. Due to the low HBV birth rate and limited resources in the sub-Saharan Africa, an effective and trustworthy strategy need to be built to achieve the goal of HBV elimination in sub-Saharan Africa. This article analyzes the current situation of prevention of the hepatitis B in the sub-Saharan region, and puts forward some intervention and prevention measures in order to provide some theoretical basis for the prevention and treatment of hepatitis B.

Keywords:

sub-Saharan Africa, prevention, hepatitis B

Li,M.;Ou,A.;Xiao,Z. (2023). Current Situation and the Challenge of Eliminating Hepatitis B in Sub-Saharan Africa. Theoretical and Natural Science,3,431-437.
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References

[1]. M. H. Nguyen, G. Wong, E. Gane, J. H. Kao, G. Dusheiko. Hepatitis B Virus: Advances in Prevention, Diagnosis, and Therapy. Clinical Microbiology Reviews. 2020;33(2).

[2]. WHO. Hepatitis Scorecard for the WHO Africa Region Implementing the hepatitis elimination strategy 2019.

[3]. WHO. Global hepatitis report, 2017. 2017.

[4]. WHO. Global health sector strategy on viral hepatitis 2016-2021. Towards ending viral hepatitis. 2016.

[5]. E. Amponsah-Dacosta. Hepatitis B virus infection and hepatocellular carcinoma in sub-Saharan Africa: Implications for elimination of viral hepatitis by 2030? World journal of Gastroenterology. 2021; 27(36):6025-38.

[6]. C. W. Spearman, M. Afihene, R. Ally, B. Apica, Y. Awuku, L. Cunha, et al. Hepatitis B in sub- Saharan Africa: strategies to achieve the 2030 elimination targets. The Lancet Gastroenterology & Hepatology. 2017; 2(12):900-9.

[7]. M. W. Sonderup, G. Dusheiko, H. Desalegn, M. Lemoine, C. Tzeuton, S. D. Taylor-Robinson, et al. Hepatitis B in sub-Saharan Africa-How many patients need therapy? Journal of Viral Hepatitis. 2020; 27(6):560-7.

[8]. J. Cohn, M. N. Owiredu, M. M. Taylor, P. Easterbrook, O. Lesi, B. Francoise, et al. Eliminating mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B in sub-Saharan Africa. Bulletin of the World Health Organization. 2021; 99(4):287-95.

[9]. WHO. hepatitis B 2022

[10]. E. Keane, A. L. Funk, Y. Shimakawa. Systematic review with meta-analysis: the risk of motherto-child transmission of hepatitis B virus infection in sub-Saharan Africa. Aliment Pharmacol Ther. 2016; 44(10):1005-17.

[11]. A. Kramvis. Challenges for hepatitis B virus cure in resource-limited settings in sub-Saharan Africa. Curr Opin HIV AIDS. 2020; 15(3):185-92.

[12]. H. Desalegn, H. Aberra, N. Berhe, B. Mekasha, K. Stene-Johansen, H. Krarup, et al. Treatment of chronic hepatitis B in sub-Saharan Africa: 1-year results of a pilot program in Ethiopia. BMC medicine. 2018; 16(1):234.

[13]. S. Anderson, L. M. Harper, J. Dionne-Odom, G. Halle-Ekane, A. T. N. Tita. A decision analytic model for prevention of hepatitis B virus infection in Sub-Saharan Africa using birth-dose vaccination. Int J Gynaecol Obstet. 2018; 141(1):126-32.

[14]. B. Malewezi, S. B. Omer, B. Mwagomba, T. Araru. Protecting health workers from nosocomial Hepatitis B infections: A review of strategies and challenges for implementation of Hepatitis B vaccination among health workers in Sub-Saharan Africa. J Epidemiol Glob Health. 2016; 6(4):229-41.

[15]. I. W. Apata, F. Averhoff, J. Pitman, A. Bjork, J. Yu, N. A. Amin, et al. Progress toward prevention of transfusion-transmitted hepatitis B and hepatitis C infection--sub-Saharan Africa, 2000-2011. MMWR Morbidity and Mortality Weekly Report. 2014; 63(29):613-9.

[16]. A. Boisson, V. Goel, M. Yotebieng, J. B. Parr, B. Fried, P. Thompson. Implementation Approaches for Introducing and Overcoming Barriers to Hepatitis B Birth-Dose Vaccine in sub-Saharan Africa. Global health, Science and Practice. 2022;10(1).

[17]. C. Béguelin, F. Fall, M. Seydi, G. Wandeler. The current situation and challenges of screening for and treating hepatitis B in sub-Saharan Africa. Expert Review of Gastroenterology & Hepatology. 2018;12(6):537-46

Cite this article

Li,M.;Ou,A.;Xiao,Z. (2023). Current Situation and the Challenge of Eliminating Hepatitis B in Sub-Saharan Africa. Theoretical and Natural Science,3,431-437.

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The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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About volume

Volume title: Proceedings of the 2nd International Conference on Biological Engineering and Medical Science (ICBioMed 2022), Part I

ISBN：978-1-915371-25-6(Print) / 978-1-915371-26-3(Online)
Editor：Gary Royle, Steven M. Lipkin
Conference website: http://www.icbiomed.org
Conference date: 7 November 2022
Series: Theoretical and Natural Science
Volume number: Vol.3
ISSN：2753-8818(Print) / 2753-8826(Online)

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References

[1]. M. H. Nguyen, G. Wong, E. Gane, J. H. Kao, G. Dusheiko. Hepatitis B Virus: Advances in Prevention, Diagnosis, and Therapy. Clinical Microbiology Reviews. 2020;33(2).

[2]. WHO. Hepatitis Scorecard for the WHO Africa Region Implementing the hepatitis elimination strategy 2019.

[3]. WHO. Global hepatitis report, 2017. 2017.

[4]. WHO. Global health sector strategy on viral hepatitis 2016-2021. Towards ending viral hepatitis. 2016.

[5]. E. Amponsah-Dacosta. Hepatitis B virus infection and hepatocellular carcinoma in sub-Saharan Africa: Implications for elimination of viral hepatitis by 2030? World journal of Gastroenterology. 2021; 27(36):6025-38.

[6]. C. W. Spearman, M. Afihene, R. Ally, B. Apica, Y. Awuku, L. Cunha, et al. Hepatitis B in sub- Saharan Africa: strategies to achieve the 2030 elimination targets. The Lancet Gastroenterology & Hepatology. 2017; 2(12):900-9.

[7]. M. W. Sonderup, G. Dusheiko, H. Desalegn, M. Lemoine, C. Tzeuton, S. D. Taylor-Robinson, et al. Hepatitis B in sub-Saharan Africa-How many patients need therapy? Journal of Viral Hepatitis. 2020; 27(6):560-7.

[8]. J. Cohn, M. N. Owiredu, M. M. Taylor, P. Easterbrook, O. Lesi, B. Francoise, et al. Eliminating mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B in sub-Saharan Africa. Bulletin of the World Health Organization. 2021; 99(4):287-95.

[9]. WHO. hepatitis B 2022

[10]. E. Keane, A. L. Funk, Y. Shimakawa. Systematic review with meta-analysis: the risk of motherto-child transmission of hepatitis B virus infection in sub-Saharan Africa. Aliment Pharmacol Ther. 2016; 44(10):1005-17.

[11]. A. Kramvis. Challenges for hepatitis B virus cure in resource-limited settings in sub-Saharan Africa. Curr Opin HIV AIDS. 2020; 15(3):185-92.

[12]. H. Desalegn, H. Aberra, N. Berhe, B. Mekasha, K. Stene-Johansen, H. Krarup, et al. Treatment of chronic hepatitis B in sub-Saharan Africa: 1-year results of a pilot program in Ethiopia. BMC medicine. 2018; 16(1):234.

[13]. S. Anderson, L. M. Harper, J. Dionne-Odom, G. Halle-Ekane, A. T. N. Tita. A decision analytic model for prevention of hepatitis B virus infection in Sub-Saharan Africa using birth-dose vaccination. Int J Gynaecol Obstet. 2018; 141(1):126-32.

[14]. B. Malewezi, S. B. Omer, B. Mwagomba, T. Araru. Protecting health workers from nosocomial Hepatitis B infections: A review of strategies and challenges for implementation of Hepatitis B vaccination among health workers in Sub-Saharan Africa. J Epidemiol Glob Health. 2016; 6(4):229-41.

[15]. I. W. Apata, F. Averhoff, J. Pitman, A. Bjork, J. Yu, N. A. Amin, et al. Progress toward prevention of transfusion-transmitted hepatitis B and hepatitis C infection--sub-Saharan Africa, 2000-2011. MMWR Morbidity and Mortality Weekly Report. 2014; 63(29):613-9.

[16]. A. Boisson, V. Goel, M. Yotebieng, J. B. Parr, B. Fried, P. Thompson. Implementation Approaches for Introducing and Overcoming Barriers to Hepatitis B Birth-Dose Vaccine in sub-Saharan Africa. Global health, Science and Practice. 2022;10(1).

[17]. C. Béguelin, F. Fall, M. Seydi, G. Wandeler. The current situation and challenges of screening for and treating hepatitis B in sub-Saharan Africa. Expert Review of Gastroenterology & Hepatology. 2018;12(6):537-46

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