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The implication and advantages of small-molecule drug
- 1 University of Shanghai for Science and Technology
- 2 University of California(Davis)
* Author to whom correspondence should be addressed.
Abstract
Small-molecule drugs are a widely used and theoretically mature therapeutic approach. Due to their small size and stable chemical structure, they can better penetrate the cell membrane and directly reach the intercellular target side, and their pharmacokinetics are more predictable. Many small-molecule drugs have contributed to medical advances and improved the lives of patients. At present, they have shown relatively high efficiency in the targeted treatment of a variety of diseases. In this review, we highlight their mechanisms and possibilities in the treatment of individual human diseases such as Alzheimer’s disease, cancer, and Covid-19 by comparing them with traditional macromolecular drugs, as well as the percentage of small molecule drugs used in current drugs, specific improvements in patient efficacy, or new insights into the mechanisms of action of small molecule drugs. For the prospects of small molecule drugs, new drugs will also emerge along with new challenges.
Keywords
Small Molecule Drug, Alzheimer’s Disease, Cancer, Covid, Tacrine
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Cite this article
Lu,T.;Yang,J. (2023). The implication and advantages of small-molecule drug. Theoretical and Natural Science,24,76-80.
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Volume title: Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
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